Leader :
Takumi Hirata, M.D., Ph.D.（Health Services Research）
Members :
Yukie Masui, Ph.D. Yuko Yoshida, Ph.D.（Health Services Research）
Kae Ito, M.D., Ph.D., Mayuko Ono, Ph.D.（Social Inclusion Studies）
Hiroki Inagaki, Ph.D.（Dementia and Mental Health Research）
Yuri Miura, Ph.D., Hiroki Tsumoto, Ph.D., Keitaro Umezawa, Ph.D., Kyojiro Kawakami, Ph.D.（Proteome Research）
Keywords
Healthy longevity; Longitudinal study; People aged 80+; Centenarian; Proteome, Genomic epidemiology; Arteriosclerosis; Aging-related diseases; Oral diseases; Oral function; Nutrition; Cognitive function; Psychological well-being; History of life; Leisure activities; Personality; Psychological strategies of adaptation
The SONIC study aims to identify aging-related changes in functional characteristics and to examine factors associated with healthy longevity among community-dwelling oldest-old adults.
The SONIC study has several strengths:
1) a comprehensive interdisciplinary study including variables regarding medical, biological, sociological, psychological, physical, and dental domains;
2) a design with sequential comparison of different age cohorts, such as ages 70, 80, 90, and 100 years (narrow age cohort study);
3) a community-based study conducted in two large geographical regions (Tokyo and Hyogo) and two subregions (an urban area and a rural area) to examine the effects of environment and lifestyle on healthy longevity.
Each age cohort is followed every 3 years except for the centenarians. The baseline surveys for the 70-year-old cohort, the 80-year-old cohort, and the 90-year-old cohort were completed in 2010, 2011, and 2012, respectively. A follow-up survey has been conducted for each age cohort since 2013. By 2024, the 70-year-old cohort, the 80-year-old cohort and the 90-year-old cohort had completed five follow-up surveys.
